ARG55412
anti-BCAP31 / BAP31 antibody
anti-BCAP31 / BAP31 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat
Cell Biology and Cellular Response antibody; Cell Death antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes BCAP31 / BAP31 |
|---|---|
| 反应物种 | Hu, Rat |
| 预测物种 | Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | BCAP31 / BAP31 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide (17 aa) within the last 50 aa of Human BCAP31. |
| 偶联标记 | Un-conjugated |
| 別名 | BAP31; Bap31; 6C6-AG; DXS1357E; CDM; BCR-associated protein 31; 6C6-AG tumor-associated antigen; p28; Protein CDM; B-cell receptor-associated protein 31; DDCH |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Ramos Cell Lysate |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS and 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P51572 Human B-cell receptor-associated protein 31 |
|---|---|
| 基因名称 | BCAP31 |
| 全名 | B-cell receptor-associated protein 31 |
| 背景介绍 | This gene encodes a member of the B-cell receptor associated protein 31 superfamily. The encoded protein is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in caspase 8-mediated apoptosis. Microdeletions in this gene are associated with contiguous ABCD1/DXS1375E deletion syndrome (CADDS), a neonatal disorder. Alternative splicing of this gene results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 16. [provided by RefSeq, Jan 2012] |
| 生物功能 | Functions as a chaperone protein. Is one of the most abundant endoplasmic reticulum (ER) proteins. Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD). Also serves as a cargo receptor for the export of transmembrane proteins. May be involved in CASP8-mediated apoptosis. [UniProt] |
| 研究领域 | Cell Biology and Cellular Response antibody; Cell Death antibody |
| 预测分子量 | 28 kDa |
| 翻译后修饰 | Cleaved by CASP8 and other caspases. |
检测图片 (2) Click the Picture to Zoom In
-
ARG55412 anti-BCAP31 / BAP31 antibody WB image
Western blot: Ramos cell lysate stained with ARG55412 anti-BCAP31 / BAP31 antibody.
-
ARG55412 anti-BCAP31 / BAP31 antibody IHC image
Immunohistochemistry: Rat lung tissue stained with ARG55412 anti-BCAP31 / BAP31 antibody at 2 µg/ml dilution.
