ARG55423
anti-BCAP31 / BAP31 antibody [1502CT208.31.16]
anti-BCAP31 / BAP31 antibody [1502CT208.31.16] for Western blot and Human
Cell Biology and Cellular Response antibody; Cell Death antibody
概述
| 产品描述 | Mouse Monoclonal antibody recognizes BCAP31 / BAP31 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 1502CT208.31.16 |
| 同位型 | IgG1, kappa |
| 靶点名称 | BCAP31 / BAP31 |
| 抗原物种 | Human |
| 抗原 | Recombinant Human BCAP31 protein. |
| 偶联标记 | Un-conjugated |
| 別名 | BAP31; Bap31; 6C6-AG; DXS1357E; CDM; BCR-associated protein 31; 6C6-AG tumor-associated antigen; p28; Protein CDM; B-cell receptor-associated protein 31; DDCH |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | A431 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P51572 Human B-cell receptor-associated protein 31 |
|---|---|
| 基因名称 | BCAP31 |
| 全名 | B-cell receptor-associated protein 31 |
| 背景介绍 | This gene encodes a member of the B-cell receptor associated protein 31 superfamily. The encoded protein is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in caspase 8-mediated apoptosis. Microdeletions in this gene are associated with contiguous ABCD1/DXS1375E deletion syndrome (CADDS), a neonatal disorder. Alternative splicing of this gene results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 16. [provided by RefSeq, Jan 2012] |
| 生物功能 | Functions as a chaperone protein. Is one of the most abundant endoplasmic reticulum (ER) proteins. Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD). Also serves as a cargo receptor for the export of transmembrane proteins. May be involved in CASP8-mediated apoptosis. [UniProt] |
| 研究领域 | Cell Biology and Cellular Response antibody; Cell Death antibody |
| 预测分子量 | 28 kDa |
| 翻译后修饰 | Cleaved by CASP8 and other caspases. |
检测图片 (1) Click the Picture to Zoom In
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ARG55423 anti-BCAP31 / BAP31 antibody WB image
Western blot: 20 µg of A431 whole cell lysate stained with ARG55423 anti-BCAP31 / BAP31 antibody at 1:2000 dilution.
