ARG44470
anti-BCAP / PIK3AP1 antibody
anti-BCAP / PIK3AP1 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes BCAP / PIK3AP1 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | BCAP / PIK3AP1 |
| 抗原物种 | Human |
| 抗原 | Human BCAP/PIK3AP1 recombinant protein |
| 偶联标记 | Un-conjugated |
| 別名 | PIK3AP1; Phosphoinositide-3-Kinase Adaptor Protein 1; BCAP; B-Cell Phosphoinositide 3-Kinase Adapter Protein 1; B-Cell Adapter For Phosphoinositide 3-Kinase; Phosphoinositide 3-Kinase Adapter Protein 1 |
应用说明
| 应用建议 |
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| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q6ZUJ8 Human Phosphoinositide 3-kinase adapter protein 1 |
|---|---|
| 基因名称 | PIK3AP1 |
| 全名 | Phosphoinositide-3-Kinase Adaptor Protein 1 |
| 背景介绍 | Predicted to enable phosphatidylinositol 3-kinase regulatory subunit binding activity and signaling receptor binding activity. Predicted to be involved in regulation of inflammatory response; regulation of signal transduction; and toll-like receptor signaling pathway. Predicted to be located in cytoplasm and membrane. Predicted to be active in cytosol. |
| 生物功能 | Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL. |
| 细胞定位 | Cell membrane, Cytoplasm, Membrane |
| 预测分子量 | 90 kDa |
| 翻译后修饰 | Phosphoprotein |
检测图片 (1) Click the Picture to Zoom In
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ARG44470 anti-BCAP / PIK3AP1 antibody WB image
Western blot: HEL stained with ARG44470 anti-BCAP / PIK3AP1 antibody at 0.5 μg/mL dilution.
