ARG63146
anti-BAIAP2 antibody
anti-BAIAP2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Neuroscience antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes BAIAP2 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Cow, Dog |
| 应用 | IHC-P, WB |
| 特异性 | This antibody will recognise only one of three reported isoforms (NP_006331.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | BAIAP2 |
| 抗原物种 | Human |
| 抗原 | C-SMSSADVEVARF |
| 偶联标记 | Un-conjugated |
| 別名 | IRS-58; Fas ligand-associated factor 3; Brain-specific angiogenesis inhibitor 1-associated protein 2; Insulin receptor substrate p53; IRSp53; BAI-associated protein 2; IRSP53; FLAF3; IRSp53/58; BAI1-associated protein 2; Insulin receptor substrate protein of 53 kDa; BAP2; Protein BAP2; Insulin receptor substrate p53/p58 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9UQB8 Human Brain-specific angiogenesis inhibitor 1-associated protein 2 |
|---|---|
| 背景介绍 | The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009] |
| 研究领域 | Neuroscience antibody |
| 预测分子量 | 61 kDa |
| 翻译后修饰 | Phosphorylated on tyrosine residues by INSR in response to insulin treatment. |
检测图片 (2) Click the Picture to Zoom In
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ARG63146 anti-BAIAP2 antibody WB image
Western blot: Human BAIAP2 with DYKDDDDK tag expressing plasmid transfected HEK293 cell lysate (10 µg sample in RIPA buffer) stained with ARG63146 anti-BAIAP2 (isoform 3) antibody at 1 µg/ml dilution (Lane A); Mock-transfected HEK293 stained with primary antibodies (Lane B). HEK293 cell lysate stained with anti-DYKDDDDK Tag at 1:3000 diluiton (Lane C). Primary antibodies were incubated at RT for 1 hour.
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ARG63146 anti-BAIAP2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human cortex tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63146 anti-BAIAP2 antibody at 3.75 µg/ml dilution followed by AP-staining.
