ARG41228
anti-BAG5 antibody
anti-BAG5 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes BAG5 |
|---|---|
| 反应物种 | Hu, Rat |
| 预测物种 | Ms, Hm |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | BAG5 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 415-429 of Human BAG5. (QGEEKCKAARKQAVR) |
| 偶联标记 | Un-conjugated |
| 別名 | BAG-5; Bcl-2-associated athanogene 5; BAG family molecular chaperone regulator 5 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | ~ 53 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Thimerosal and 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q5QJC9 Rat BAG family molecular chaperone regulator 5 Swiss-port # Q9UL15 Human BAG family molecular chaperone regulator 5 |
|---|---|
| 基因名称 | BAG5 |
| 全名 | BCL2-associated athanogene 5 |
| 背景介绍 | The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2 (By similarity). May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding. [UniProt] |
| 预测分子量 | 51 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG41228 anti-BAG5 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human placenta tissue stained with ARG41228 anti-BAG5 antibody.
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ARG41228 anti-BAG5 antibody WB image
Western blot: Rat thymus, Rat spleen, Rat testis and PANC cell lysates stained with ARG41228 anti-BAG5 antibody.
