ARG42653
anti-Arylsulfatase A antibody
anti-Arylsulfatase A antibody for Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Arylsulfatase A |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Arylsulfatase A |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 210-509 of Human Arylsulfatase A (NP_000478.3). |
| 偶联标记 | Un-conjugated |
| 別名 | ASA; Cerebroside-sulfatase; EC 3.1.6.8; Arylsulfatase A; MLD |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | A549 and Mouse testis | ||||
| 实际分子量 | ~ 62 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ARSA |
| 全名 | arylsulfatase A |
| 背景介绍 | The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2010] |
| 生物功能 | Hydrolyzes cerebroside sulfate. [UniProt] |
| 细胞定位 | Lysosome. [UniProt] |
| 预测分子量 | 54 kDa |
| 翻译后修饰 | The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. This post-translational modification is severely defective in multiple sulfatase deficiency (MSD). [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG42653 anti-Arylsulfatase A antibody WB image
Western blot: 25 µg of A549 cell lysate stained with ARG42653 anti-Arylsulfatase A antibody at 1:1000 dilution.
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ARG42653 anti-Arylsulfatase A antibody WB image
Western blot: 25 µg of Mouse testis lysate stained with ARG42653 anti-Arylsulfatase A antibody at 1:1000 dilution.
