ARG66110
anti-Artemin antibody
anti-Artemin antibody for ELISA,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Artemin |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Artemin |
| 抗原物种 | Human |
| 抗原 | E. coli derived recombinant Human Artemin. (AGGPGSRARA AGARGCRLRS QLVPVRALGL GHRSDELVRF RFCSGSCRRA RSPHDLSLAS LLGAGALRPP PGSRPVSQPC CRPTRYEAVS FMDVNSTWRT VDRLSATACG CLG) |
| 偶联标记 | Un-conjugated |
| 別名 | ENOVIN; Neublastin; EVN; Artemin; Enovin; NBN |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ARTN |
| 全名 | artemin |
| 背景介绍 | The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008] |
| 生物功能 | Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue. [UniProt] |
| 预测分子量 | 23 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG66110 anti-Artemin antibody WB image
Western blot: 250 - 0.24 ng of Human Artemin stained with ARG66110 anti-Artemin antibody, under non-reducing conditions.
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ARG66110 anti-Artemin antibody standard curve image
Sandwich ELISA: ARG66110 anti-Artemin antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG66111 anti-Artemin antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density reading at 405 - 650 nm.
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ARG66110 anti-Artemin antibody WB image
Western blot: 250 - 0.24 ng of Human Artemin stained with ARG66110 anti-Artemin antibody, under reducing conditions.
