ARG66525
anti-Arginase 1 antibody
anti-Arginase 1 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes Arginase 1 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2b, kappa |
| 靶点名称 | Arginase 1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from Human Arginase 1. |
| 偶联标记 | Un-conjugated |
| 別名 | EC 3.5.3.1; Type I arginase; Arginase-1; Liver-type arginase |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: EDTA buffer (pH 8.0) was used. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol and 0.5% BSA |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ARG1 |
| 全名 | arginase 1 |
| 背景介绍 | Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
| 细胞定位 | Cytoplasm. Cytoplasmic granule. Note=Localized in azurophil granules of neutrophils (PubMed:15546957). [UniProt] |
| 预测分子量 | 35 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG66525 anti-Arginase 1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human hepatocellular carcinoma stained with ARG66525 anti-Arginase 1 antibody at 1:200 (4°C, overnight). Antigen Retrieval: EDTA buffer (pH 8.0) was used.
