ARG23488
anti-Aquaporin 1 antibody [7D11]
anti-Aquaporin 1 antibody [7D11] for ELISA,Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Mouse Monoclonal antibody [7D11] recognizes Aquaporin 1. Mouse anti Aquaporin 1 antibody, clone 7D11 recognizes an epitope within an extracellular region of the water-specific channel aquaporin 1 (also known as AQP1 or CHIP-28)Aquaporin 1 is a 28kDa integral membrane protein which was originally identified in red blood cells and renal proximal tubules. AQP1 is also expressed by the choroid plexus and various other tissues. The glycosylated forms of AQP1 range between 40-60kDa in mass. |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ELISA, FACS, IHC-P, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 7D11 |
| 同位型 | IgG2b |
| 靶点名称 | Aquaporin 1 |
| 抗原物种 | Rat |
| 抗原 | Synthetic peptide around aa. 198-208 of Rat Aquaporin 1. |
| 偶联标记 | Un-conjugated |
| 別名 | Aquaporin-1; CO; AQP-CHIP; AQP-1; Aquaporin-CHIP; Water channel protein for red blood cells and kidney proximal tubule; CHIP28; Urine water channel |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: Boil tissue section in Sodium citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS, 0.1% Sodium azide and 0.1% BSA. |
| 抗菌剂 | 0.1% Sodium azide |
| 稳定剂 | 0.1% BSA |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | AQP1 |
| 全名 | aquaporin 1 (Colton blood group) |
| 背景介绍 | Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This gene encodes an aquaporin which functions as a molecular water channel protein. It is a homotetramer with 6 bilayer spanning domains and N-glycosylation sites. The protein physically resembles channel proteins and is abundant in erythrocytes and renal tubes. The gene encoding this aquaporin is a possible candidate for disorders involving imbalance in ocular fluid movement. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] |
| 生物功能 | Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. [UniProt] |
| 预测分子量 | 29 kDa |
