ARG43958
anti-Apolipoprotein E antibody
anti-Apolipoprotein E antibody for ELISA,Flow cytometry,ICC/IF,Western blot and Human
概述
产品描述 | Rabbit Polyclonal antibody recognizes Apolipoprotein E |
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反应物种 | Hu |
应用 | ELISA, FACS, ICC/IF, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | Apolipoprotein E |
抗原物种 | Human |
抗原 | Human Apolipoprotein E recombinant protein |
表达系统 | E.coli |
偶联标记 | Un-conjugated |
Protein Full name | Apolipoprotein E |
別名 | APOE; Apolipoprotein E; AD2; Alzheimer Disease 2 (APOE*E4-Associated, Late Onset); Apolipoprotein E3; LDLCQ5; APO-E; ApoE4; Apo-E; LPG |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Affinity purified with Immunogen. |
缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
稳定剂 | 4% Trehalose |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | APOE |
全名 | Apolipoprotein E |
背景介绍 | The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. |
生物功能 | APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. |
细胞定位 | Chylomicron, Endosome, Extracellular matrix, HDL, Secreted, VLDL |
预测分子量 | 36 kDa |
翻译后修饰 | Glycation, Glycoprotein, Oxidation, Phosphoprotein |
检测图片 (3) Click the Picture to Zoom In
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ARG43958 anti-Apolipoprotein E antibody ICC/IF image
Immunofluorescence: U2OS cells stained with ARG43958 anti-Apolipoprotein E antibody at 5 μg/ml dilution.
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ARG43958 anti-Apolipoprotein E antibody WB image
Western blot: Caco-2 stained with ARG43958 anti-Apolipoprotein E antibody at 0.5 μg/mL dilution.
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ARG43958 anti-Apolipoprotein E antibody FACS image
Flow Cytometry: Coca-2 cells stained with ARG43958 anti-Apolipoprotein E antibody (blue) at 1 μg/1x10^6 cells dilution.