ARG67237
anti-Apolipoprotein AI antibody [3A10]
anti-Apolipoprotein AI antibody [3A10] for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [3A10] recognizes Apolipoprotein AI |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 3A10 |
| 同位型 | IgG1 |
| 靶点名称 | Apolipoprotein AI |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | APOA1; Apolipoprotein A1; Apolipoprotein A-I; Apo-AI; Epididymis Secretory Sperm Binding Protein; AMYLD3; HPALP2; Apo(A); ApoA-I |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | PBS (pH 7.0), 0.025% ProClin 300 and 20% Glycerol. |
| 抗菌剂 | 0.025% ProClin 300 |
| 稳定剂 | 20% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | APOA1 |
| 全名 | Apolipoprotein A1 |
| 背景介绍 | This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015] |
| 生物功能 | Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. [Uniprot] |
| 细胞定位 | Amyloid, HDL, Secreted. [Uniprot] |
| 预测分子量 | 31 kDa |
| 翻译后修饰 | Glycation, Glycoprotein, Lipoprotein, Oxidation, Palmitate, Phosphoprotein. [Uniprot] |
检测图片 (3) Click the Picture to Zoom In
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ARG67237 anti-Apolipoprotein AI antibody [3A10] IHC-P image
Immunohistochemistry: Human Hepatocellular carcinoma stained with ARG67237 anti-Apolipoprotein AI antibody [3A10] at 1:200 dilution.
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ARG67237 anti-Apolipoprotein AI antibody [3A10] ICC/IF image
Immunofluorescence: HepG2 stained with ARG67237 anti-Apolipoprotein AI antibody [3A10] at 1:200 dilution.
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ARG67237 anti-Apolipoprotein AI antibody [3A10] WB image
Western blot: Human serum stained with ARG67237 anti-Apolipoprotein AI antibody [3A10] at 1:1000 dilution.
