ARG65669

anti-Annexin A2 antibody

anti-Annexin A2 antibody for Western blot and Human,Mouse

Signaling Transduction antibody

概述

产品描述 Goat Polyclonal antibody recognizes Annexin A2
反应物种 Hu, Ms
预测物种 Cow, Rat, Pig
应用 WB
特异性 This antibody is expected to recognise both reported isoforms. NP_004030.1, NP_001002857.1 and NP_001129487.1 are varients of isoform 2.
宿主 Goat
克隆 Polyclonal
同位型 IgG
靶点名称 Annexin A2
抗原物种 Human
抗原 Synthetic peptide around the N-terminus of Human Annexin A2 (STVHEILCKLSLEGD)
偶联标记 Un-conjugated
別名 Placental anticoagulant protein IV; LPC2; Protein I; Calpactin-1 heavy chain; Calpactin I heavy chain; p36; CAL1H; ANX2; LPC2D; Lipocortin II; ANX2L4; HEL-S-270; LIP2; Annexin II; Annexin A2; Annexin-2; P36; Chromobindin-8; PAP-IV

应用说明

应用建议
应用 推荐稀释比
WB0.5 - 3 µg/ml
应用说明 WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purified from goat serum by antigen affinity chromatography.
缓冲液 Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 0.5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 12306 Mouse ANXA2

GeneID: 302 Human ANXA2

Swiss-port # P07355 Human Annexin A2

Swiss-port # P07356 Mouse Annexin A2

基因名称 ANXA2
全名 annexin A2
背景介绍 This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
生物功能 Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9 [UniProt]
研究领域 Signaling Transduction antibody
预测分子量 39 kDa
翻译后修饰 Phosphorylation of Tyr-24 enhances heat stress-induced translocation to the cell surface.
ISGylated.

检测图片 (1) Click the Picture to Zoom In

  • ARG65669 anti-Annexin A2 antibody WB image

    Western Blot: A431 lysate (RIPA buffer, 35 µg total protein per lane) stained with ARG65669 anti-Annexin A2 antibody at 0.5 µg/ml dilution.