ARG43265
anti-Angiopoietin 4 antibody
anti-Angiopoietin 4 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Angiopoietin 4 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Angiopoietin 4 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from Human Angiopoietin 4. |
| 偶联标记 | Un-conjugated |
| 別名 | AGP4; Angiopoietin-3; Angiopoietin-4; ANG4; ANG-3; ANG-4 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | ~ 55 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 纯度 | > 95% (by SDS-PAGE). |
| 缓冲液 | PBS (pH 7.2), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ANGPT4 |
| 全名 | angiopoietin 4 |
| 背景介绍 | Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The mechanism by which they contribute to angiogenesis is thought to involve regulation of endothelial cell interactions with supporting perivascular cells. The protein encoded by this gene functions as an agonist and is an angiopoietin. [provided by RefSeq, Jul 2008] |
| 生物功能 | Binds to TEK/TIE2, modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2. Promotes endothelial cell survival, migration and angiogenesis. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 57 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG43265 anti-Angiopoietin 4 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human stomach carcinoma tissue stained with ARG43265 anti-Angiopoietin 4 antibody at 1:50 dilution (left). Negative control: Using PBS instead of primary antibody (right).
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ARG43265 anti-Angiopoietin 4 antibody WB image
Western blot: 40 µg of HCC827, H460 and H1792 whole cell lysates stained with ARG43265 anti-Angiopoietin 4 antibody at 1:500 dilution.
