ARG55438
anti-Aldolase antibody
anti-Aldolase antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Cancer antibody; Metabolism antibody; Signaling Transduction antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Aldolase |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 预测物种 | Rb |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Aldolase |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 66-95 (N-terminus) of Human Aldolase. |
| 偶联标记 | Un-conjugated |
| 別名 | Lung cancer antigen NY-LU-1; HEL-S-87p; GSD12; Fructose-bisphosphate aldolase A; Muscle-type aldolase; EC 4.1.2.13; ALDA |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | 293 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ALDOA |
| 全名 | aldolase A, fructose-bisphosphate |
| 背景介绍 | The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Aug 2011] |
| 生物功能 | Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity). [UniProt] |
| 细胞定位 | Cytoplasm, myofibril, sarcomere, I band. Cytoplasm, myofibril, sarcomere, M line. Note=In skeletal muscle, accumulates around the M line and within the I band, colocalizing with FBP2 on both sides of the Z line in the absence of Ca(2+) |
| 研究领域 | Cancer antibody; Metabolism antibody; Signaling Transduction antibody |
| 预测分子量 | 39 kDa |
检测图片 (3) Click the Picture to Zoom In
-
ARG55438 anti-Aldolase antibody ICC/IF image
Immunofluorescence: HepG2 cells stained with ARG55438 anti-Aldolase antibody (green). DAPI (blue) for nuclear staining.
-
ARG55438 anti-Aldolase antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human lung carcinoma tissue stained with ARG55438 anti-Aldolase antibody.
-
ARG55438 anti-Aldolase antibody WB image
Western blot: 35 µg of 293 cell lysate stained with ARG55438 anti-Aldolase antibody at 1:1000 dilution.
