概述

产品描述	Rabbit Polyclonal antibody recognizes ATRIP
反应物种	Hu, Ms, Rat
应用	ICC/IF, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	ATRIP
抗原物种	Human
抗原	Synthetic peptide derived from Human ATRIP.
偶联标记	Un-conjugated
別名	ATR-interacting protein; ATM and Rad3-related-interacting protein

应用说明

应用建议	应用 推荐稀释比 ICC/IF 1:50 - 1:200 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	PC-3
实际分子量	~ 88 kDa

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 235610 Mouse ATRIP GeneID: 84126 Human ATRIP Swiss-port # Q8BMG1 Mouse ATR-interacting protein Swiss-port # Q8WXE1 Human ATR-interacting protein
基因名称	ATRIP
全名	ATR interacting protein
背景介绍	This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012]
生物功能	Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein. [UniProt]
细胞定位	Nucleus. Note=Redistributes to discrete nuclear foci upon DNA damage. [UniProt]
预测分子量	86 kDa
翻译后修饰	Phosphorylated by ATR. [UniProt]

检测图片 (1) Click the Picture to Zoom In