概述

产品描述	Rabbit Polyclonal antibody recognizes ATP5O
反应物种	Hu, Ms, Rat
应用	ICC/IF, IHC-P, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	ATP5O
抗原物种	Human
抗原	Recombinant Protein of Human ATP5O.
偶联标记	Un-conjugated
別名	Oligomycin sensitivity conferral protein; ATP synthase subunit O, mitochondrial; ATPO; HMC08D05; OSCP

应用说明

应用建议	应用 推荐稀释比 ICC/IF 1:50 - 1:200 IHC-P 1:50 - 1:200 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	MCF7

属性

形式	Liquid
纯化	Affinity purification with immunogen.
缓冲液	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 192241 Rat ATP5O GeneID: 28080 Mouse ATP5O GeneID: 539 Human ATP5O Swiss-port # P48047 Human ATP synthase subunit O, mitochondrial Swiss-port # Q06647 Rat ATP synthase subunit O, mitochondrial Swiss-port # Q9DB20 Mouse ATP synthase subunit O, mitochondrial More
基因名称	ATP5O
全名	ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
背景介绍	The protein encoded by this gene is a component of the F-type ATPase found in the mitochondrial matrix. F-type ATPases are composed of a catalytic core and a membrane proton channel. The encoded protein appears to be part of the connector linking these two components and may be involved in transmission of conformational changes or proton conductance. [provided by RefSeq, Jul 2008]
生物功能	Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. [UniProt]
预测分子量	23 kDa
翻译后修饰	Acetylation at Lys-162 decreases ATP production. Deacetylated by SIRT3.

检测图片 (1) Click the Picture to Zoom In