ARG58316
anti-ATP2A3 / SERCA3 ATPase antibody
anti-ATP2A3 / SERCA3 ATPase antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ATP2A3 / SERCA3 ATPase |
|---|---|
| 反应物种 | Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ATP2A3 / SERCA3 ATPase |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to a sequence at the N-terminus of Human ATP2A3(1-30aa MEAAHLLPAADVLRHFSVTAEGGLSPAQVT), different from the related Mouse sequence by five amino acids, and from the related Rat sequence by six amino acids. |
| 偶联标记 | Un-conjugated |
| 別名 | SERCA3; SR Ca; Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; EC 3.6.3.8; Calcium pump 3; 2+ |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: By heat mediation. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P18596 Rat Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 Swiss-port # Q64518 Mouse Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 |
|---|---|
| 基因名称 | ATP2A3 |
| 全名 | ATPase, Ca++ transporting, ubiquitous |
| 背景介绍 | This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| 生物功能 | This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction. [UniProt] |
| 细胞定位 | Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 114 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG58316 anti-ATP2A3 / SERCA3 ATPase antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse thymus stained with ARG58316 anti-ATP2A3 / SERCA3 ATPase antibody.
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ARG58316 anti-ATP2A3 / SERCA3 ATPase antibody WB image
Western blot: 50 µg of Rat skeletal muscle and Mouse skeletal muscle lysates stained with ARG58316 anti-ATP2A3 / SERCA3 ATPase antibody at 0.5 µg/ml dilution.
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ARG58316 anti-ATP2A3 / SERCA3 ATPase antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat thymus stained with ARG58316 anti-ATP2A3 / SERCA3 ATPase antibody.
