ARG43466
anti-ATG16L1 antibody
anti-ATG16L1 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ATG16L1. |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ATG16L1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from human ATG16L1 |
| 偶联标记 | Un-conjugated |
| Protein Full name | Autophagy-related protein 16-1 |
| 別名 | IBD10; WDR30; APG16L; ATG16A; ATG16L |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ATG16L1 |
| 全名 | autophagy related 16-like 1 |
| 背景介绍 | The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2010] |
| 生物功能 | Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane. [UniProt] |
检测图片 (5) Click the Picture to Zoom In
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ARG43466 anti-ATG16L1 antibody IHC-P image
Immunohistochemistry: Human colon stained with ARG43466 anti-ATG16L1 antibody at 1:100 dilution.
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ARG43466 anti-ATG16L1 antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG43466 anti-ATG16L1 antibody at 1:100 dilution.
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ARG43466 anti-ATG16L1 antibody WB image
Western blot: HT-29, MCF7 and HeLa stained with ARG43466 anti-ATG16L1 antibody at 1:1000 dilution.
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ARG43466 anti-ATG16L1 antibody ICC/IF image
Immunofluorescence: H9c2 stained with ARG43466 anti-ATG16L1 antibody at 1:100 dilution.
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ARG43466 anti-ATG16L1 antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG43466 anti-ATG16L1 antibody at 1:100 dilution.
