ARG58220
anti-ASIC2 antibody
anti-ASIC2 antibody for Western blot and Human,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ASIC2 |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ASIC2 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 112-147 of Human ACCN1. (ELLALLDVNLQIPDPHLADPSVLEALRQKANFKHYK) |
| 偶联标记 | Un-conjugated |
| 別名 | ACCN1; ACCN; BNC1; Amiloride-sensitive cation channel 1, neuronal; MDEG; Mammalian degenerin homolog; Amiloride-sensitive cation channel neuronal 1; BNaC1; ASIC2; Amiloride-sensitive brain sodium channel; Acid-sensing ion channel 2; hBNaC1; ASIC2a; Brain sodium channel 1 |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ASIC2 |
| 全名 | acid sensing (proton gated) ion channel 2 |
| 背景介绍 | This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Feb 2012] |
| 生物功能 | Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate. [UniProt] |
| 细胞定位 | Cell membrane; Multi-pass membrane protein. Localized at the plasma membrane of neurons, in the soma and punctated peripheral processes. [UniProt] |
| 预测分子量 | 58 kDa |
检测图片 (1) Click the Picture to Zoom In
-
ARG58220 anti-ASIC2 antibody WB image
Western blot: Rat testis and MCF-7 whole cell lysates stained with ARG58220 anti-ASIC2 antibody at 0.5 µg/ml dilution.
