ARG44004
anti-ASC / TMS1 antibody
anti-ASC / TMS1 antibody for ELISA,Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ASC / TMS1 |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ASC / TMS1 |
| 抗原物种 | Human |
| 抗原 | Human ASC / TMS1 recombinant protein |
| 表达系统 | E.coli |
| 偶联标记 | Un-conjugated |
| Protein Full name | Apoptosis-associated speck-like protein containing a CARD |
| 別名 | PYCARD; PYD And CARD Domain Containing; CARD5; ASC; Apoptosis-Associated Speck-Like Protein Containing A CARD; TMS-1; Caspase Recruitment Domain-Containing Protein 5; Target Of Methylation-Induced Silencing 1; TMS1; PYD And CARD Domain-Containing Protein; Apoptosis-Associated Speck-Like; HASC; TMS |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9ULZ3 Human Apoptosis-associated speck-like protein containing a CARD |
|---|---|
| 基因名称 | PYCARD |
| 全名 | PYD And CARD Domain Containing |
| 背景介绍 | This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. |
| 生物功能 | Functions as key mediator in apoptosis and inflammation. |
| 细胞定位 | Cytoplasm, Endoplasmic reticulum, Golgi apparatus, Inflammasome, Membrane, Mitochondrion, Nucleus |
| 预测分子量 | 22 kDa |
| 翻译后修饰 | Isopeptide bond, Phosphoprotein, Ubl conjugation |
检测图片 (4) Click the Picture to Zoom In
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ARG44004 anti-ASC / TMS1 antibody IHC-P image
Immunohistochemistry: Human urothelial carcinoma stained with ARG44004 anti-ASC / TMS1 antibody at 2 μg/ml dilution.
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ARG44004 anti-ASC / TMS1 antibody WB image
Western blot:THP-1 and HL-6 stained withARG44004 anti-ASC / TMS1 antibody at 0.5 μg/mL dilution.
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ARG44004 anti-ASC / TMS1 antibody ICC/IF image
Immunofluorescence: A549 cells stained with ARG44004 anti-ASC / TMS1 antibody at 5 μg/ml dilution.
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ARG44004 anti-ASC / TMS1 antibody FACS image
Flow Cytometry: THP-1 cells stained with ARG44004 anti-ASC / TMS1 antibody (blue) at 1 μg/1x10^6 cells dilution.
