ARG41366
anti-ARPC5 / p16 ARC antibody
anti-ARPC5 / p16 ARC antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat
参考文献2
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ARPC5 / p16 ARC |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ARPC5 / p16 ARC |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from Human ARPC5 / p16 ARC. |
| 偶联标记 | Un-conjugated |
| 別名 | p16-Arc; p16-ARC; Actin-related protein 2/3 complex subunit 5; ARC16; Arp2/3 complex 16 kDa subunit; dJ127C7.3 |
应用说明
| 应用建议 |
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | ~ 17 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ARPC5 |
| 全名 | actin related protein 2/3 complex, subunit 5, 16kDa |
| 背景介绍 | This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] |
| 生物功能 | Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. [UniProt] |
| 细胞定位 | Cytoplasm, cytoskeleton. Cell projection. [UniProt] |
| 预测分子量 | 16 kDa |
| 翻译后修饰 | Polyubiquitinated by RNF128 with 'Lys-63'-linked chains, leading to proteasomal degradation. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
-
ARG41366 anti-ARPC5 / p16 ARC antibody ICC/IF image
Immunofluorescence: Neuro-2a cells stained with ARG41366 anti-ARPC5 / p16 ARC antibody (green). DAPI (blue) for nuclear staining.
-
ARG41366 anti-ARPC5 / p16 ARC antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human colon tissue stained with ARG41366 anti-ARPC5 / p16 ARC antibody.
-
ARG41366 anti-ARPC5 / p16 ARC antibody WB image
Western blot: Human fetal brain lysate stained with ARG41366 anti-ARPC5 / p16 ARC antibody.
文献引用
Melatonin receptor 1A/B knockout accelerates atrial aging in mice
IHC-P / Mouse
Melatonin alleviates aging-related heart failure through melatonin receptor 1A/B knockout in mice
IHC-P / Mouse
