ARG55160
anti-ARP2 antibody
anti-ARP2 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Cancer antibody; Signaling Transduction antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ARP2 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Bov, Chk, Xenopus |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ARP2 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 191-219 (Center) of Human ARP2. |
| 偶联标记 | Un-conjugated |
| 別名 | Actin-related protein 2; Actin-like protein 2; ARP2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | HeLa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ACTR2 |
| 全名 | ARP2 actin-related protein 2 homolog (yeast) |
| 背景介绍 | The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. [UniProt] |
| 细胞定位 | Cytoplasm, cytoskeleton. Cell projection |
| 研究领域 | Cancer antibody; Signaling Transduction antibody |
| 预测分子量 | 45 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG55160 anti-ARP2 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human skeletal muscle stained with ARG55160 anti-ARP2 antibody.
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ARG55160 anti-ARP2 antibody WB image
Western blot: 35 µg of HeLa cell lysate stained with ARG55160 anti-ARP2 antibody.
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ARG55160 anti-ARP2 antibody FACS image
Flow Cytometry: A375 cells stained with ARG55160 anti-ARP2 antibody (right histogram) or without primary antibody control (left histogram), followed by incubation with FITC labelled secondary antibody.
