ARG64382
anti-ARNO / cytohesin 2 antibody
anti-ARNO / cytohesin 2 antibody for Western blot and Human
Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes ARNO / cytohesin 2 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Dog |
| 应用 | WB |
| 特异性 | This antibody is expected to recognise both reported isoforms (NP_004219.2; NP_059431.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ARNO / cytohesin 2 |
| 抗原物种 | Human |
| 抗原 | EDGVYEPPDLTP-C |
| 偶联标记 | Un-conjugated |
| 別名 | Sec7p-like; Protein ARNO; CTS18; Cytohesin-2; PH, SEC7 and coiled-coil domain-containing protein 2; ARF nucleotide-binding site opener; Sec7p-L; PSCD2; SEC7L; ARNO; ARF exchange factor; PSCD2L; CTS18.1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 实际分子量 | ~ 47 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] |
| 研究领域 | Signaling Transduction antibody |
| 预测分子量 | 47 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG64382 anti-ARNO / cytohesin 2 antibody WB image
Western blot: 35 µg of Human brain (cerebellum) lysate (in RIPA buffer) stained with ARG64382 anti-ARNO / cytohesin 2 antibody at 0.5 µg/ml dilution and incubated at RT for 1 hour.
