ARG41291

anti-ARL4A antibody

anti-ARL4A antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes ARL4A
反应物种 Hu, Ms, Rat
应用 ICC/IF, IHC-P
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 ARL4A
抗原物种 Human
抗原 Recombinant fusion protein corresponding to aa. 121-200 of Human ARL4A (NP_001032241.1).
偶联标记 Un-conjugated
別名 ARL4; ADP-ribosylation factor-like protein 4A

应用说明

应用建议
应用 推荐稀释比
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purified.
缓冲液 PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 10124 Human ARL4A

GeneID: 11861 Mouse ARL4A

GeneID: 29308 Rat ARL4A

基因名称 ARL4A
全名 ADP-ribosylation factor-like 4A
背景介绍 ADP-ribosylation factor-like 4A is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4A is similar to ARL4C and ARL4D and each has a nuclear localization signal and an unusually high guaninine nucleotide exchange rate. ARL4A is located in both the nuclear and extranuclear cell compartments. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
生物功能 Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form. [UniProt]
细胞定位 Cell membrane. Cytoplasm. Nucleus, nucleolus. Note=Localization in the nucleolus is dependent by nucleotide binding. [UniProt]
预测分子量 23 kDa
翻译后修饰 Myristoylated. [UniProt]

检测图片 (2) Click the Picture to Zoom In

  • ARG41291 anti-ARL4A antibody ICC/IF image

    Immunofluorescence: NIH/3T3 cells stained with ARG41291 anti-ARL4A antibody at 1:100 dilution.

  • ARG41291 anti-ARL4A antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human liver cancer tissue stained with ARG41291 anti-ARL4A antibody at 1:100 dilution.