ARG45241
anti-ARL13B antibody
anti-ARL13B antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Polyclonal antibody recognizes ARL13B |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ARL13B |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human ARL13B. |
| 偶联标记 | Un-conjugated |
| 別名 | ARL13B; ARF Like GTPase 13B; ADP Ribosylation Factor Like GTPase 13B; ARL2L1; JBTS8; ADP-Ribosylation Factor-Like Protein 13B; ADP-Ribosylation Factor-Like 2-Like 1; ARL2-Like Protein 1; DKFZp761H079; ADP-Ribosylation Factor-Like Protein 2-Like 1; ADP-Ribosylation Factor Like GTPase 13B; ADP-Ribosylation Factor-Like 13B |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 55 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q3SXY8 Human ADP-ribosylation factor-like protein 13B Swiss-port # Q640N2 Mouse ADP-ribosylation factor-like protein 13B |
|---|---|
| 基因名称 | ARL13B |
| 全名 | ARF Like GTPase 13B |
| 背景介绍 | This gene encodes a member of the ADP-ribosylation factor-like family. The encoded protein is a small GTPase that contains both N-terminal and C-terminal guanine nucleotide-binding motifs. This protein is localized in the cilia and plays a role in cilia formation and in maintenance of cilia. Mutations in this gene are the cause of Joubert syndrome 8. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] |
| 生物功能 | Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze fit; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex. Plays a role in ciliar trafficking of phosphatidylinositol phosphatase INPP5E in ciliogenesis. [UniProt] |
| 细胞定位 | Cell membrane ; Cell projection ; Cilium ; Cytoplasm ; Cytoskeleton ; Membrane. [UniProt] |
| 预测分子量 | 49 kDa |
| 翻译后修饰 | Isopeptide bond ; Lipoprotein ; Palmitate ; Ubl conjugation. [UniProt] |
检测图片 (6) Click the Picture to Zoom In
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ARG45241 anti-ARL13B antibody IHC-P image
Immunohistochemistry: Human breast cancer stained with ARG45241 anti-ARL13B antibody at 2 μg/ml dilution.
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ARG45241 anti-ARL13B antibody ICC/IF image
Immunofluorescence: U20S stained with ARG45241 anti-ARL13B antibody at 5 ug/ml dilution.
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ARG45241 anti-ARL13B antibody WB image
Western blot: 293T stained with ARG45241 anti-ARL13B antibody at 0.5 μg/ml dilution.
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ARG45241 anti-ARL13B antibody FACS image
Flow Cytometry: K562 stained with ARG45241 anti-ARL13B antibody at 1 µg/10^6 cells dilution.
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ARG45241 anti-ARL13B antibody WB image
Western blot: Rat brain stained with ARG45241 anti-ARL13B antibody at 0.5 μg/ml dilution.
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ARG45241 anti-ARL13B antibody WB image
Western blot: Mouse brain stained with ARG45241 anti-ARL13B antibody at 0.5 μg/ml dilution.
