ARG65768
anti-ARHGEF5 antibody
anti-ARHGEF5 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ARHGEF5 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ARHGEF5 |
| 抗原物种 | Human |
| 抗原 | Fusion protein of Human ARHGEF5 (NP_005426.2) |
| 偶联标记 | Un-conjugated |
| 別名 | P60; TIM1; Oncogene TIM; Rho guanine nucleotide exchange factor 5; TIM; GEF5; Ephexin-3; p60 TIM; Transforming immortalized mammary oncogene; Guanine nucleotide regulatory protein TIM |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 40% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q12774 Human Rho guanine nucleotide exchange factor 5 |
|---|---|
| 基因名称 | ARHGEF5 |
| 全名 | Rho guanine nucleotide exchange factor (GEF) 5 |
| 背景介绍 | Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq, Jul 2008] |
| 预测分子量 | 177 kDa |
| 翻译后修饰 | Activation of SRC induces tyrosine phosphorylation of ARHGEF5. |
检测图片 (3) Click the Picture to Zoom In
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ARG65768 anti-ARHGEF5 antibody IHC-P image
Immunohistochemistry: paraffin-embedded Human thyroid cancer tissue stained with ARG65768 anti-ARHGEF5 antibody (left) at 1:50 dilution, or the same antibody pre-incubated with antigen (right). (Original magnification: X200)
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ARG65768 anti-ARHGEF5 antibody WB image
Western blot: 40 µg of 1) HeLa, 2) K562 cell lysates statined with ARG65768 anti-ARHGEF5 antibody at 1:1150 dilution.
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ARG65768 anti-ARHGEF5 antibody IHC-P image
Immunohistochemistry: paraffin-embedded Human brain tissue stained with ARG65768 anti-ARHGEF5 antibody (left) at 1:50 dilution, or the same antibody pre-incubated with antigen (right). (Original magnification: X200)
