ARG44625
anti-ARHGEF1 antibody
anti-ARHGEF1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes ARHGEF1 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, IP |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2b |
| 靶点名称 | ARHGEF1 |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | ARHGEF1; Rho Guanine Nucleotide Exchange Factor 1; P115-RHOGEF; SUB1.5; LBCL2; Rho Guanine Nucleotide Exchange Factor (GEF) 1; 115 KDa Guanine Nucleotide Exchange Factor; P115RhoGEF; 115-KD Protein; Lsc Homolog; P115-RhoGEF; Sub1.5; IMD62; GEF1; LSC |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q92888 Human Rho guanine nucleotide exchange factor 1 |
|---|---|
| 基因名称 | ARHGEF1 |
| 全名 | Rho Guanine Nucleotide Exchange Factor 1 |
| 背景介绍 | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008] |
| 生物功能 | Mediates angiotensin-2-induced RhoA activation. [UniProt] |
| 细胞定位 | Cytoplasm, Membrane. [UniProt] |
| 预测分子量 | 102 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG44625 anti-ARHGEF1 antibody IHC-P image
Immunohistochemistry: Human spleen stained with ARG44625 anti-ARHGEF1 antibody at 5 µg/mL dilution.
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ARG44625 anti-ARHGEF1 antibody IP image
Immunoprecipitation: HEK-293 lysate immunoprecipitated with 2.5 µg of ARG44625 anti-ARHGEF1 antibody.
