ARG58088
anti-ARHGDIB antibody
anti-ARHGDIB antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ARHGDIB |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ARHGDIB |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-201 of Human ARHGDIB (NP_001166.3). |
| 偶联标记 | Un-conjugated |
| 別名 | RhoGDI2; Rho-GDI beta; RAP1GN1; Rho GDP-dissociation inhibitor 2; GDID4; LYGDI; Ly-GDI; Rho GDI 2; D4; GDIA2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse brain | ||||||
| 实际分子量 | 23 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ARHGDIB |
| 全名 | Rho GDP dissociation inhibitor (GDI) beta |
| 背景介绍 | Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).[supplied by OMIM, Dec 2010] |
| 生物功能 | Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 23 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG58088 anti-ARHGDIB antibody WB image
Western blot: 25 µg of Mouse brain lysate stained with ARG58088 anti-ARHGDIB antibody at 1:1000 dilution.
