ARG45581
anti-APPL1 antibody
anti-APPL1 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes APPL1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | APPL1 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human APPL1. |
| 偶联标记 | Un-conjugated |
| 別名 | APPL1; Adaptor Protein, Phosphotyrosine Interacting With PH Domain And Leucine Zipper 1; APPL; DCC-Interacting Protein 13-Alpha; Adaptor Protein, Phosphotyrosine Interaction, PH Domain And Leucine Zipper Containing 1; Adapter Protein Containing PH Domain, PTB Domain And Leucine Zipper Motif 1; Dip13-Alpha; Adaptor Protein Containing PH Domain, PTB Domain And Leucine Zipper Motif 1; Signaling Adaptor Protein DIP13alpha; AKT2 Interactor; DIP13alpha; KIAA1428; MODY14; DIP13A |
应用说明
| 应用建议 |
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 85 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | APPL1 |
| 全名 | Adaptor Protein, Phosphotyrosine Interacting With PH Domain And Leucine Zipper 1 |
| 背景介绍 | The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008] |
| 生物功能 | Multifunctional adapter protein that binds to various membrane receptors, nuclear factors and signaling proteins to regulate many processes, such as cell proliferation, immune response, endosomal trafficking and cell metabolism. [UniProt] |
| 细胞定位 | Cell projection; Cytoplasm; Cytoplasmic vesicle; Endosome; Membrane; Nucleus. [UniProt] |
| 预测分子量 | 80 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
检测图片 (6) Click the Picture to Zoom In
-
ARG45581 anti-APPL1 antibody IHC-P image
Immunohistochemistry: Human tonsil stained with ARG45581 anti-APPL1 antibody at 1 μg/ml dilution.
-
ARG45581 anti-APPL1 antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG45581 anti-APPL1 antibody at 5 μg/ml dilution.
-
ARG45581 anti-APPL1 antibody WB image
Western blot: Hela stained with ARG45581 anti-APPL1 antibody at 0.5 μg/ml dilution.
-
ARG45581 anti-APPL1 antibody FACS image
Flow Cytometry: A549 stained with ARG45581 anti-APPL1 antibody at 1 µg/10^6 cells dilution.
-
ARG45581 anti-APPL1 antibody WB image
Western blot: Rat brain stained with ARG45581 anti-APPL1 antibody at 0.5 μg/ml dilution.
-
ARG45581 anti-APPL1 antibody WB image
Western blot: Mouse brain stained with ARG45581 anti-APPL1 antibody at 0.5 μg/ml dilution.
