ARG64741
anti-APOBEC3G antibody
anti-APOBEC3G antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Gene Regulation antibody; Immune System antibody; Microbiology and Infectious Disease antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes APOBEC3G |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | APOBEC3G |
| 抗原物种 | Human |
| 抗原 | C-DEHSQDLSGRLR |
| 偶联标记 | Un-conjugated |
| 別名 | ARP-9; APOBEC-related cytidine deaminase; Deoxycytidine deaminase; APOBEC-related protein; dJ494G10.1; DNA dC->dU-editing enzyme APOBEC-3G; CEM-15; CEM15; ARCD; ARP9; APOBEC-related protein 9; EC 3.5.4.-; A3G; bK150C2.7; MDS019 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9HC16 Human DNA dC->dU-editing enzyme APOBEC-3G |
|---|---|
| 背景介绍 | This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. The protein encoded by this gene has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity. [provided by RefSeq, Jul 2008] |
| 研究领域 | Gene Regulation antibody; Immune System antibody; Microbiology and Infectious Disease antibody |
| 预测分子量 | 46 kDa |
| 翻译后修饰 | Ubiquitinated in the presence of HIV-1 VIF. Association with VIF targets the protein for proteolysis by the ubiquitin-dependent proteasome pathway. Phosphorylation at Thr-32 reduces its binding to HIV-1 VIF and subsequent ubiquitination and degradation thus promoting its antiviral activity. |
检测图片 (3) Click the Picture to Zoom In
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ARG64741 anti-APOBEC3G antibody WB image
Western Blot: Daudi lysate (35µg protein in RIPA buffer) stained with ARG64741 anti-APOBEC3G antibody (0.5µg/ml)
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ARG64741 anti-APOBEC3G antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human testis tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64741 anti-APOBEC3G antibody at 2.5 µg/ml dilution followed by AP-staining.
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ARG64741 anti-APOBEC3G antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human kidney tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64741 anti-APOBEC3G antibody at 2.5 µg/ml dilution followed by AP-staining.
