ARG46013
anti-APOBEC3G antibody
anti-APOBEC3G antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes APOBEC3G |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | APOBEC3G |
| 抗原物种 | Human |
| 抗原 | A 15 amino acid synthetic peptide within the first 50 amino acids of human APOBEC3G. |
| 偶联标记 | Un-conjugated |
| 別名 | APOBEC3G; ARP-9; APOBEC-related cytidine deaminase; Deoxycytidine deaminase; APOBEC-related protein; dJ494G10.1; DNA dC->dU-editing enzyme APOBEC-3G; CEM-15; CEM15; ARCD; ARP9; APOBEC-related protein 9; EC 3.5.4.-; A3G; bK150C2.7; MDS019 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 纯化 | Affinity chromatography purified |
|---|---|
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9HC16 Human DNA dC->dU-editing enzyme APOBEC-3G |
|---|---|
| 基因名称 | APOBEC3G |
| 全名 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| 背景介绍 | This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. The protein encoded by this gene has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity. [provided by RefSeq, Jul 2008] |
| 预测分子量 | 46 kDa |
| 翻译后修饰 | Ubiquitinated in the presence of HIV-1 VIF. Association with VIF targets the protein for proteolysis by the ubiquitin-dependent proteasome pathway. Phosphorylation at Thr-32 reduces its binding to HIV-1 VIF and subsequent ubiquitination and degradation thus promoting its antiviral activity. |
