ARG46004
anti-APBA2 antibody
anti-APBA2 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes APBA2 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | APBA2 |
| 抗原物种 | Human |
| 抗原 | A 18 amino acid synthetic peptide within aa. 290 - 340 of human APBA2. |
| 偶联标记 | Un-conjugated |
| 別名 | amyloid beta (A4) precursor protein-binding, family A, member 2; APBA2; X11L; MINT2; LIN-10; HsT16821; X11-BETA; D15S1518E; MGC:14091; X11L; Amyloid beta A4 precursor protein-binding family A member 2; Adapter protein X11beta; Mint-2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 纯化 | Affinity chromatography purified |
|---|---|
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -54°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q99767 Human Amyloid beta A4 precursor protein-binding family A member 2 |
|---|---|
| 基因名称 | APBA2 |
| 全名 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| 背景介绍 | The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2017] |
| 生物功能 | Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta. [UniProt] |
| 预测分子量 | 83 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
