ARG46002
anti-AP3S1 antibody
anti-AP3S1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes AP3S1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | AP3S1 |
| 抗原物种 | Human |
| 抗原 | A 19 amino acid synthetic peptide within the first 50 amino acids of human AP3S1. |
| 偶联标记 | Un-conjugated |
| 別名 | adaptor-related protein complex 3, sigma 1 subunit; AP3S1; CLAPS3; Sigma3A; CLAPS3; AP-3 complex subunit sigma-1; AP-3 complex subunit sigma-3A; Sigma3A-adaptin |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 纯化 | Affinity chromatography purified |
|---|---|
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -52°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | AP3S1 |
| 全名 | adaptor-related protein complex 3, sigma 1 subunit |
| 背景介绍 | This gene encodes a subunit of the AP3 adaptor complex. This complex functions in the formation of subcellular vesicles budded from the Golgi body. Several related pseudogenes of this gene have been found. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015] |
| 生物功能 | Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. [UniProt] |
| 细胞定位 | Golgi apparatus. Cytoplasmic vesicle; Membrane. [UniProt] |
| 预测分子量 | 22 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
