ARG41196
anti-AP1M2 antibody
anti-AP1M2 antibody for ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes AP1M2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | AP1M2 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 164-423 of Human AP1M2 (NP_005489.2). |
| 偶联标记 | Un-conjugated |
| 別名 | HSMU1B; Golgi adaptor HA1/AP1 adaptin mu-2 subunit; MU-1B; Mu-adaptin 2; AP-mu chain family member mu1B; mu2; Adaptor-related protein complex 1 subunit mu-2; Clathrin assembly protein complex 1 mu-2 medium chain 2; MU1B; Mu1B-adaptin; AP-1 complex subunit mu-2; AP1-mu2; Adaptor protein complex AP-1 subunit mu-2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse kidney | ||||||
| 实际分子量 | 48 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | AP1M2 |
| 全名 | adaptor-related protein complex 1, mu 2 subunit |
| 背景介绍 | This gene encodes a subunit of the heterotetrameric adaptor-related protein comlex 1 (AP-1), which belongs to the adaptor complexes medium subunits family. This protein is capable of interacting with tyrosine-based sorting signals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
| 生物功能 | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. [UniProt] |
| 细胞定位 | Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. [UniProt] |
| 预测分子量 | 48 kDa |
| 翻译后修饰 | Phosphorylation of membrane-bound AP1M1/AP1M2 increases its affinity for sorting signals. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG41196 anti-AP1M2 antibody WB image
Western blot: 25 µg of Mouse kidney lysate stained with ARG41196 anti-AP1M2 antibody at 1:1000 dilution.
