ARG40888
anti-ANP32A / PHAP1 antibody
anti-ANP32A / PHAP1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
产品描述 | Rabbit Polyclonal antibody recognizes ANP32A / PHAP1 |
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反应物种 | Hu, Ms, Rat |
应用 | IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | ANP32A / PHAP1 |
抗原物种 | Human |
抗原 | Recombinant fusion protein corresponding to aa. 1-170 of Human ANP32A (NP_006296.1). |
偶联标记 | Un-conjugated |
別名 | Putative HLA-DR-associated protein I; Potent heat-stable protein phosphatase 2A inhibitor I1PP2A; Mapmodulin; pp32; PHAPI; C15orf1; PP32; I1PP2A; PHAP1; Acidic nuclear phosphoprotein pp32; LANP; Acidic leucine-rich nuclear phosphoprotein 32 family member A; HPPCn; MAPM; Leucine-rich acidic nuclear protein |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
阳性对照 | Raji | ||||||
实际分子量 | 28 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | ANP32A |
全名 | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
生物功能 | Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1-mediated transcriptional repression. [UniProt] |
细胞定位 | Cytoplasm, Endoplasmic reticulum, Nucleus. [UniProt] |
预测分子量 | 29 kDa |
翻译后修饰 | Phosphorylated on serine residues. The N-terminus is blocked. Some glutamate residues are glycylated by TTLL8. This modification occurs exclusively on glutamate residues and results in a glycine chain on the gamma-carboxyl group (By similarity). [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG40888 anti-ANP32A / PHAP1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse brain tissue stained with ARG40888 anti-ANP32A / PHAP1 antibody at 1:100 dilution.
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ARG40888 anti-ANP32A / PHAP1 antibody WB image
Western blot: 25 ug of Raji cell lysate stained with ARG40888 anti-ANP32A / PHAP1 antibody at 1:1000 dilution.