ARG66456
anti-ANKRD1 antibody
anti-ANKRD1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ANKRD1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 预测物种 | Bov, Chk, Pig, Rb |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ANKRD1 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide within the C-terminal region of Human ANKRD1. |
| 偶联标记 | Un-conjugated |
| 別名 | bA320F15.2; CVARP; ALRP; CARP; Cardiac ankyrin repeat protein; Cytokine-inducible nuclear protein; Cytokine-inducible gene C-193 protein; C-193; MCARP; Ankyrin repeat domain-containing protein 1 |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: Heat mediation was performed in Sodium citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 实际分子量 | 40 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.42% Potassium phosphate (pH 7.3), 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 30% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ANKRD1 |
| 全名 | ankyrin repeat domain 1 (cardiac muscle) |
| 背景介绍 | The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system. [provided by RefSeq, Jul 2008] |
| 生物功能 | May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 36 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG66456 anti-ANKRD1 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human lymph node. Antigen Retrieval: Heat mediation was performed in Sodium citrate buffer (pH 6.0). The section was then incubated with ARG66456 anti-ANKRD1 antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
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ARG66456 anti-ANKRD1 antibody WB image
Western blot: HeLa, Jurkat, NIH/3T3 and H9C2 whole cell lysates stained with ARG66456 anti-ANKRD1 antibody.
