ARG45334
anti-ANGPT4 antibody [2H34]
anti-ANGPT4 antibody [2H34] for IHC-Formalin-fixed paraffin-embedded sections and Mouse
概述
产品描述 | Rat Monoclonal antibody [2H34] recognizes ANGPT4 |
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反应物种 | Ms |
应用 | IHC-P |
宿主 | Rat |
克隆 | Monoclonal |
克隆号 | 2H34 |
同位型 | IgG2 |
靶点名称 | ANGPT4 |
抗原物种 | Mouse |
抗原 | Recombinant Mouse ANGPT4 . |
偶联标记 | Un-conjugated |
別名 | ANGPT4; Angiopoietin 4; Angiopoietin-4; ANG3; ANG4; Angiopoietin-3; ANG-4; ANG-3 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Protein G chromatography |
缓冲液 | PBS |
浓度 | 0.1 - 1.0 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | ANGPT4 |
全名 | Angiopoietin 4 |
背景介绍 | Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The mechanism by which they contribute to angiogenesis is thought to involve regulation of endothelial cell interactions with supporting perivascular cells. The protein encoded by this gene functions as an agonist and is an angiopoietin. [provided by RefSeq, Jul 2008] |
生物功能 | Binds to TEK/TIE2, modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2. Promotes endothelial cell survival, migration and angiogenesis. [UniProt] |
细胞定位 | Secreted. [UniProt] |
预测分子量 | 58 kDa |
翻译后修饰 | Disulfide bond; Glycoprotein. [UniProt] |
检测图片 (1) Click the Picture to Zoom In