ARG44531
anti-ANAPC1 antibody
anti-ANAPC1 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Ectodermal dysplasia, Hypotrichosis
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ANAPC1 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ANAPC1 |
| 抗原物种 | Human |
| 抗原 | Human ANAPC1 recombinant protein |
| 偶联标记 | Un-conjugated |
| 別名 | ANAPC1; Anaphase Promoting Complex Subunit 1; TSG24; APC1; MCPR; Anaphase-Promoting Complex Subunit 1; Testis-Specific Gene 24 Protein; Mitotic Checkpoint Regulator; Cyclosome Subunit 1 |
应用说明
| 应用建议 |
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| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9H1A4 Human Anaphase-promoting complex subunit 1 |
|---|---|
| 基因名称 | ANAPC1 |
| 全名 | Anaphase Promoting Complex Subunit 1 |
| 背景介绍 | This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. |
| 生物功能 | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. |
| 研究领域 | Ectodermal dysplasia, Hypotrichosis |
| 预测分子量 | 217 kDa |
| 翻译后修饰 | Phosphoprotein |
检测图片 (4) Click the Picture to Zoom In
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ARG44531 anti-ANAPC1 antibody IHC-P image
Immunohistochemistry: Human placenta stained with ARG44531 anti-ANAPC1 antibody at 2 μg/mL dilution.
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ARG44531 anti-ANAPC1 antibody ICC/IF image
Immunofluorescence: MCF-7 stained with ARG44531 anti-ANAPC1 antibody at 5 μg/mL dilution.
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ARG44531 anti-ANAPC1 antibody WB image
Western blot: HEK293 and K562 stained with ARG44531 anti-ANAPC1 antibody at 0.5 μg/mL dilution.
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ARG44531 anti-ANAPC1 antibody FACS image
Flow Cytometry: A549 stained with ARG44531 anti-ANAPC1 antibody at 1 μg/10^6 cells dilution.
