ARG45148
anti-AMHR2 antibody
anti-AMHR2 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes AMHR2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | AMHR2 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to C-terminal region of human AMHR2. |
| 偶联标记 | Un-conjugated |
| 別名 | AMHR2; anti-Mullerian hormone receptor, type II; MISRII; EC 2.7.11.30; MRII; AMHR; MIS type II receptor; AMH type II receptor; Anti-Muellerian hormone type-2 receptor; MISR2; Anti-Muellerian hormone type II receptor |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 65 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | AMHR2 |
| 全名 | anti-Mullerian hormone receptor, type II |
| 背景介绍 | This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2009] |
| 生物功能 | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. [UniProt] |
| 细胞定位 | Membrane. [UniProt] |
| 预测分子量 | 63 kDa |
| 翻译后修饰 | Disulfide bond; Glycoprotein. [UniProt] |
检测图片 (6) Click the Picture to Zoom In
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ARG45148 anti-AMHR2 antibody IHC-P image
Immunohistochemistry: Human ovarian cancer stained with ARG45148 anti-AMHR2 antibody at 1 μg/ml dilution.
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ARG45148 anti-AMHR2 antibody ICC/IF image
Immunofluorescence: CACO-2 stained with ARG45148 anti-AMHR2 antibody at 5 ug/ml dilution.
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ARG45148 anti-AMHR2 antibody WB image
Western blot: 293T, MCF-7, and HL-60 stained with ARG45148 anti-AMHR2 antibody at 0.5 μg/ml dilution.
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ARG45148 anti-AMHR2 antibody FACS image
Flow Cytometry: K562 stained with ARG45148 anti-AMHR2 antibody at 1 µg/10^6 cells dilution.
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ARG45148 anti-AMHR2 antibody IHC-P image
Immunohistochemistry: Rat testis stained with ARG45148 anti-AMHR2 antibody at 1 μg/ml dilution.
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ARG45148 anti-AMHR2 antibody IHC-P image
Immunohistochemistry: Mouse testis stained with ARG45148 anti-AMHR2 antibody at 1 μg/ml dilution.
