ARG11105
anti-AMH antibody [AMH41cc]
anti-AMH antibody [AMH41cc] for Chemiluminescence immunoassay,ELISA,IHC-Formalin-fixed paraffin-embedded sections,Purification,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [AMH41cc] recognizes AMH |
|---|---|
| 反应物种 | Hu |
| 应用 | CLIA, ELISA, IHC-P, Puri, WB |
| 特异性 | Mullerian hormone |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | AMH41cc |
| 同位型 | IgG2a |
| 靶点名称 | AMH |
| 抗原物种 | Human |
| 抗原 | Recombinant Human AMH. |
| 偶联标记 | Un-conjugated |
| 別名 | AMH; Muellerian-inhibiting substance; MIF; Anti-Muellerian hormone; Muellerian-inhibiting factor; MIS |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | Sandwich ELISA (Capture antibody - Detection antibody): ARG11106 - ARG11105 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS (pH 7.4) and 0.09% Sodium azide. |
| 抗菌剂 | 0.09% Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | AMH |
| 全名 | anti-Mullerian hormone |
| 背景介绍 | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2016] |
| 生物功能 | This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 59 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG11105 anti-AMH antibody [AMH41cc] CLIA image
Calibration curves for recombinant AMH in sandwich CLIA using ARG11106 - ARG11105 (Capture antibody - Detection antibody). The label used was streptavidin/HRP. Recombinant antigen was diluted with PBS containing 0.1% Tween 20 and 75 mg/ml BSA.
