ARG44041
anti-AMBRA1 antibody
anti-AMBRA1 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes AMBRA1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | AMBRA1 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein containing a sequence corresponding to amino acids 1109-1208 of Human Ambra1 (NP_060219.2). |
| 偶联标记 | Un-conjugated |
| 別名 | DCAF3; Activating molecule in BECN1-regulated autophagy protein 1; WDR94 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # A2AH22 Mouse Activating molecule in BECN1-regulated autophagy protein 1 Swiss-port # Q9C0C7 Human Activating molecule in BECN1-regulated autophagy protein 1 |
|---|---|
| 基因名称 | AMBRA1 |
| 全名 | autophagy/beclin-1 regulator 1 |
| 背景介绍 | Enables GTPase binding activity and ubiquitin protein ligase binding activity. Involved in macroautophagy; positive regulation of phosphatidylinositol 3-kinase activity; and response to mitochondrial depolarisation. Located in cytosol. Colocalizes with mitochondrion. Biomarker of multiple system atrophy. |
| 生物功能 | Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation (By similarity). [UniProt] |
| 细胞定位 | Autophagosome. Note: Localizes also to discrete punctae along the ciliary axoneme. [UniProt] |
| 预测分子量 | 143 kDa |
检测图片 (4) Click the Picture to Zoom In
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ARG44041 anti-AMBRA1 antibody IHC-P image
Immunohistochemistry: Rat lung stained with ARG44041 anti-AMBRA1 antibody at 1:100 dilution.
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ARG44041 anti-AMBRA1 antibody ICC/IF image
Immunofluorescence: NIH/3T3 stained with ARG44041 anti-AMBRA1 antibody at 1:50 dilution.
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ARG44041 anti-AMBRA1 antibody WB image
Western blot: PANC-1 stained with ARG44041 anti-AMBRA1 antibody at 1:800 dilution.
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ARG44041 anti-AMBRA1 antibody IHC-P image
Immunohistochemistry: Mouse lung stained with ARG44041 anti-AMBRA1 antibody at 1:100 dilution.
