ARG43818
anti-ALP / Alkaline Phosphatase antibody
anti-ALP / Alkaline Phosphatase antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ALP / Alkaline Phosphatase |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, IP, WB |
| 特异性 | Human,Mouse,Rat |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ALP / Alkaline Phosphatase |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of human Alkaline Phosphatase. |
| 偶联标记 | Un-conjugated |
| Protein Full name | Alkaline phosphatase, tissue-nonspecific isozyme |
| 別名 | ALPL; Alkaline Phosphatase, Biomineralization Associated; TNSALP; TNALP; TNAP; Alkaline Phosphatase, Tissue-Nonspecific Isozyme; Alkaline Phosphatase Liver/Bone/Kidney Isozyme; Tissue Non-Specific Alkaline Phosphatase; Alkaline Phosphatase, Liver/Bone/Kidney; Phosphocreatine Phosphatase; Phosphoamidase; EC 3.1.3.1; AP-TNAP; TNS-ALP; HOPS; Liver/Bone/Kidney-Type Alkaline Phosphatase; Tissue-Nonspecific ALP; EC 3.9.1.1; APTNAP; HPPA; HPPC; HPPI; HPPO |
应用说明
| 应用建议 |
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| 实际分子量 | 75 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity Purified |
| 缓冲液 | PBS, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 抗菌剂 | 0.02% sodium azide |
| 稳定剂 | 50% glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ALPL |
| 全名 | Alkaline Phosphatase, Biomineralization Associated |
| 背景介绍 | This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. [provided by RefSeq, Oct 2015] |
| 生物功能 | Plays an essential role in skeletal and dental mineralization via its ability to hydrolyze extracellular diphosphate, a potent mineralization inhibitor, to phosphate: it thereby promotes hydroxyapatite crystal formation and increases inorganic phosphate concentration. [UniProt] |
| 细胞定位 | Cell membrane, Membrane, Mitochondrion. [UniProt] |
| 预测分子量 | 57 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein, GPI-anchor, Lipoprotein, Phosphoprotein. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG43818 anti-ALP / Alkaline Phosphatase antibody ICC/IF image
Immunofluorescence: HeLa cells stained with ARG43818 anti-ALP / Alkaline Phosphatase antibody at 1:50 dilution.
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ARG43818 anti-ALP / Alkaline Phosphatase antibody IHC-P image
Immunofluorescence: Human liver stained with ARG43818 anti-ALP / Alkaline Phosphatase at 1:50 dilution.
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ARG43818 anti-ALP / Alkaline Phosphatase antibody WB image
Western blot: SKOV-3, Jurkat and MCF-7 stained with ARG43818 anti-ALP / Alkaline Phosphatase antibody at 1:500 dilution.
