概述

产品描述	Rabbit Polyclonal antibody recognizes ALKBH7
反应物种	Hu, Ms, Rat
应用	WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	ALKBH7
抗原物种	Human
抗原	Recombinant Protein of Human ALKBH7.
偶联标记	Un-conjugated
別名	Spermatogenesis-associated protein 11; SPATA11; UNQ6002; Alkylated DNA repair protein alkB homolog 7; ABH7; EC 1.14.11.-; Spermatogenesis cell proliferation-related protein; Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial

应用说明

应用建议	应用 推荐稀释比 WB 1:200 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	Mouse eye

属性

形式	Liquid
纯化	Affinity purification with immunogen.
缓冲液	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 66400 Mouse ALKBH7 GeneID: 84266 Human ALKBH7 Swiss-port # Q9BT30 Human Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial Swiss-port # Q9D6Z0 Mouse Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial
基因名称	ALKBH7
全名	alkB, alkylation repair homolog 7 (E. coli)
生物功能	May function as protein hydroxylase; can catalyze auto-hydroxylation at Leu-110 (in vitro), but this activity may be due to the absence of the true substrate. Required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death. ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage. Does not display DNA demethylase activity. Involved in fatty acid metabolism (By similarity). [UniProt]
预测分子量	25 kDa

检测图片 (1) Click the Picture to Zoom In