ARG58351
anti-ALDH7A1 antibody
anti-ALDH7A1 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ALDH7A1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ALDH7A1 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 430-539 of Human ALDH7A1 (NP_001173.2). |
| 偶联标记 | Un-conjugated |
| 別名 | Alpha-AASA dehydrogenase; P6c dehydrogenase; Alpha-aminoadipic semialdehyde dehydrogenase; Antiquitin-1; ATQ1; EC 1.2.1.8; Delta1-piperideine-6-carboxylate dehydrogenase; Betaine aldehyde dehydrogenase; Aldehyde dehydrogenase family 7 member A1; EC 1.2.1.31; EPD; PDE; EC 1.2.1.3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Rat kidney | ||||||||
| 实际分子量 | 58 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ALDH7A1 |
| 全名 | aldehyde dehydrogenase 7 family, member A1 |
| 背景介绍 | The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified. [provided by RefSeq, Jan 2011] |
| 生物功能 | Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism. [UniProt] |
| 细胞定位 | Cytoplasm, Mitochondrion, Nucleus, cytosol,. [UniProt] |
| 预测分子量 | 58 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG58351 anti-ALDH7A1 antibody WB image
Western blot: 25 µg of Rat kidney lysate stained with ARG58351 anti-ALDH7A1 antibody at 1:1000 dilution.
