ARG57061
anti-ALDH5A1 antibody [17F5]
anti-ALDH5A1 antibody [17F5] for ICC/IF,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [17F5] recognizes ALDH5A1 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 17F5 |
| 同位型 | IgG2a, kappa |
| 靶点名称 | ALDH5A1 |
| 抗原物种 | Human |
| 抗原 | Recombinant fragment around aa. 48-535 of Human ALDH5A1. |
| 偶联标记 | Un-conjugated |
| 別名 | SSDH; SSADH; NAD; +; Aldehyde dehydrogenase family 5 member A1; EC 1.2.1.24; Succinate-semialdehyde dehydrogenase, mitochondrial |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 10% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P51649 Human Succinate-semialdehyde dehydrogenase, mitochondrial |
|---|---|
| 基因名称 | ALDH5A1 |
| 全名 | aldehyde dehydrogenase 5 family, member A1 |
| 背景介绍 | This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). [UniProt] |
| 预测分子量 | 57 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG57061 anti-ALDH5A1 antibody [17F5] ICC/IF image
Immunoflorescense: 293T cell line stained with ARG57061 anti-ALDH5A1 antibody [17F5] at 1:100 (Green).
DAPI (Blue) for nucleus staining.
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ARG57061 anti-ALDH5A1 antibody [17F5] WB image
Western blot: 40 µg of HepG2 cell lysate stained with ARG57061 anti-ALDH5A1 antibody [17F5] at 1:1000.
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ARG57061 anti-ALDH5A1 antibody [17F5] WB image
Western blot: 40 µg of Mouse liver tissue extract stained with ARG57061 anti-ALDH5A1 antibody [17F5] at 1:1000.
