ARG58664
anti-ALDH1A2 antibody
anti-ALDH1A2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ALDH1A2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ALDH1A2 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-180 of Human ALDH1A2 (NP_733797.1). |
| 偶联标记 | Un-conjugated |
| 別名 | RALDH; RALDH2-T; RalDH2; Retinal dehydrogenase 2; RALDH(II); RALDH 2; RALDH2; EC 1.2.1.36; II; Aldehyde dehydrogenase family 1 member A2; Retinaldehyde-specific dehydrogenase type 2 |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | 293T | ||||||||
| 实际分子量 | 57 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ALDH1A2 |
| 全名 | aldehyde dehydrogenase 1 family, member A2 |
| 背景介绍 | This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2011] |
| 生物功能 | Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently (By similarity). [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 57 kDa |
检测图片 (2) Click the Picture to Zoom In
-
ARG58664 anti-ALDH1A2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat kidney stained with ARG58664 anti-ALDH1A2 antibody at 1:100 dilution.
-
ARG58664 anti-ALDH1A2 antibody WB image
Western blot: 25 µg of 293T cell lysate stained with ARG58664 anti-ALDH1A2 antibody at 1:1000 dilution.
