ARG55354
anti-ALDH1A1 antibody
anti-ALDH1A1 antibody for ICC/IF,Western blot and Human,Rat
Cancer antibody; Developmental Biology antibody; Neuroscience antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ALDH1A1 |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ALDH1A1 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 306-339 (Center) of Human ALDH1A1. |
| 偶联标记 | Un-conjugated |
| 別名 | HEL-S-53e; RalDH1; Aldehyde dehydrogenase family 1 member A1; Retinal dehydrogenase 1; HEL-9; RALDH 1; ALDH1; Aldehyde dehydrogenase, cytosolic; ALDH11; EC 1.2.1.36; RALDH1; HEL12; PUMB1; ALHDII; ALDC; ALDH-E1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | A549 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ALDH1A1 |
| 全名 | aldehyde dehydrogenase 1 family, member A1 |
| 背景介绍 | The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011] |
| 生物功能 | Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid (By similarity). [UniProt] |
| 细胞定位 | Cytoplasm. |
| 研究领域 | Cancer antibody; Developmental Biology antibody; Neuroscience antibody |
| 预测分子量 | 55 kDa |
| 翻译后修饰 | The N-terminus is blocked most probably by acetylation. |
检测图片 (2) Click the Picture to Zoom In
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ARG55354 anti-ALDH1A1 antibody ICC/IF image
Immunofluorescence: A549 cells stained with ARG55354 anti-ALDH1A1 antibody (green) at 1:25 dilution. Cytoplasmic actin was counterstained with Alexa Fluor® 555 conjugated with Phalloidin (red).
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ARG55354 anti-ALDH1A1 antibody WB image
Western blot: 35 µg of A549 cell lysate stained with ARG55354 anti-ALDH1A1 antibody at 1:1000 dilution.
