ARG45714

anti-ALAS2 / ASB antibody

anti-ALAS2 / ASB antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes ALAS2 / ASB
反应物种 Hu, Ms, Rat
应用 FACS, ICC/IF, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 ALAS2 / ASB
抗原物种 Human
抗原 Recombinant protein containing to human ALAS2 / ASB.
偶联标记 Un-conjugated
別名 ALAS2; 5'-Aminolevulinate Synthase 2; ALAS-E; ASB; 5-Aminolevulinate Synthase, Erythroid-Specific, Mitochondrial; Erythroid-Specific Delta-Aminolevulinate Synthase; Aminolevulinate, Delta-, Synthase 2; 5-Aminolevulinic Acid Synthase 2; Delta-Aminolevulinate Synthase 2; Delta-ALA Synthase 2; EC 2.3.1.37  47; ALASE; Aminolevulinate, Delta-, Synthase 2 (Sideroblastic/Hypochromic Anemia); Sideroblastic/Hypochromic Anemia; Delta-ALA Synthetase; SIDBA1; XLDPP; XLEPP; ANH1; XLSA

应用说明

应用建议
应用 推荐稀释比
FACS1 - 3 µg/10^6 cells
ICC/IF5 μg/ml
WB0.25-0.5 μg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量 65 kDa

属性

形式 Liquid
纯化 Affinity purified
缓冲液 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
稳定剂 4% Trehalose
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 11656 Mouse ALAS2

GeneID: 212 Human ALAS2

GeneID: 25748 Rat ALAS2

基因名称 ALAS2
全名 5'-Aminolevulinate Synthase 2
背景介绍 The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
生物功能 Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products. [UniProt]
细胞定位 Membrane; Mitochondrion; Mitochondrion inner membrane. [UniProt]
预测分子量 65 kDa

检测图片 (5) Click the Picture to Zoom In

  • ARG45714 anti-ALAS2 / ASB antibody ICC/IF image

    Immunofluorescence: PC-3 stained with ARG45714 anti-ALAS2 / ASB antibody at 5 μg/ml dilution.

  • ARG45714 anti-ALAS2 / ASB antibody WB image

    Western blot: 293T stained with ARG45714 anti-ALAS2 / ASB antibody at 0.5 μg/ml dilution.

  • ARG45714 anti-ALAS2 / ASB antibody FACS image

    Flow Cytometry: K562 stained with ARG45714 anti-ALAS2 / ASB antibody at 1 µg/10^6 cells dilution.

  • ARG45714 anti-ALAS2 / ASB antibody WB image

    Western blot: Rat heart stained with ARG45714 anti-ALAS2 / ASB antibody at 0.5 μg/ml dilution.

  • ARG45714 anti-ALAS2 / ASB antibody WB image

    Western blot: Mouse liver stained with ARG45714 anti-ALAS2 / ASB antibody at 0.5 μg/ml dilution.