概述

产品描述	Rabbit Polyclonal antibody recognizes ALAS1
反应物种	Hu
应用	ICC/IF, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	ALAS1
抗原物种	Human
抗原	Synthetic peptide derived from Human Alas1.
偶联标记	Un-conjugated
別名	Delta-aminolevulinate synthase 1; 5-aminolevulinic acid synthase 1; ALASH; Delta-ALA synthase 1; ALAS3; 5-aminolevulinate synthase, nonspecific, mitochondrial; ALAS-H; MIG4; ALAS; EC 2.3.1.37

应用说明

应用建议	应用 推荐稀释比 ICC/IF 1:50 - 1:200 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	HepG2
实际分子量	~ 71 kDa

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 211 Human ALAS1 Swiss-port # P13196 Human 5-aminolevulinate synthase, nonspecific, mitochondrial
基因名称	ALAS1
全名	5'-aminolevulinate synthase 1
背景介绍	This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
细胞定位	Mitochondrion matrix. [UniProt]
预测分子量	71 kDa

检测图片 (1) Click the Picture to Zoom In