ARG63964
anti-AKR1C4 antibody
anti-AKR1C4 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Cancer antibody; Metabolism antibody; Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes AKR1C4 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 特异性 | This antibody may cross-react with AKR1C1 |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | AKR1C4 |
| 抗原物种 | Human |
| 抗原 | DPKYQRVELNDGH-C |
| 偶联标记 | Un-conjugated |
| 別名 | EC 1.1.1.357; CHDR; Aldo-keto reductase family 1 member C4; 3-alpha-HSD1; Chlordecone reductase; EC 1.1.1.225; DD-4; EC 1.1.1.-; HAKRA; 3-alpha-HSD; CDR; 3-alpha-hydroxysteroid dehydrogenase type I; C11; DD4; Dihydrodiol dehydrogenase 4 |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P17516 Human Aldo-keto reductase family 1 member C4 |
|---|---|
| 背景介绍 | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008] |
| 研究领域 | Cancer antibody; Metabolism antibody; Signaling Transduction antibody |
| 预测分子量 | 37 kDa |
| 翻译后修饰 | The N-terminus is blocked. |
检测图片 (2) Click the Picture to Zoom In
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ARG63964 anti-AKR1C4 antibody WB image
Western Blot: human liver lysate (35 µg protein in RIPA buffer) stained with ARG63964 anti-AKR1C4 antibody at 0.1 µg/ml dilution.
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ARG63964 anti-AKR1C4 antibody IHC-P image
Immunohistochemistry: paraffin embedded Human Liver. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63964 anti-AKR1C4 antibody at 2.5 µg/ml dilution followed by AP-staining.
